Erik A. Lundquist

The paper identifies domain-specific mutations in UNC-6/Netrin that differentially affect dorsal-ventral axon guidance in C. elegans.

The paper identifies EFN-4/Ephrin as a key regulator of posterior Q neuroblast migration in C. elegans and shows it converges with SAX-3/Robo, UNC-6/Netrin, and HSPG signaling in this process.

The paper uses single-cell RNA sequencing to map the transcriptomic changes in the C. elegans Q neuroblast lineage during migration and differentiation, identifying novel genes and Wnt-related mechanisms.

This paper identifies three MAB-5 target genes that control distinct stages of posterior neuroblast migration in C. elegans, linking migration to differentiation.

This study investigates the short- and long-range roles of UNC-6/Netrin in dorsal-ventral axon guidance in C. elegans, showing that UNC-6 acts as a permissive cue rather than an instructive one.

The paper identifies genes regulated by MAB-5 in C. elegans Q neuroblasts, showing cwn-1/Wnt is downstream of MAB-5 in posterior migration.

This paper identifies a short isoform of the UNC-5 receptor in C. elegans that is required for dorsal growth cone polarity and protrusion, distinct from the long isoform's inhibitory role.

This study investigates the role of SRC-1 in growth cone polarity and protrusion in C. elegans, showing it acts with UNC-5 in these processes.

This study shows that TOM-1 inhibits growth cone protrusion by regulating vesicle fusion, working with UNC-5 to restrict protrusion in C. elegans.

The paper investigates how MAX-1 inhibits UNC-5 activity to regulate VD growth cone protrusion in C. elegans, showing MAX-1 mutants have smaller, less protrusive growth cones compared to unc-5 mutants.

The paper identifies ETR-1/CELF1 RNA targets in C. elegans body wall muscle, revealing roles in muscle physiology and neuronal migration.

This study identifies DPY-17 and SQT-3 Collagens as regulators of left-right asymmetric migration of Q neuroblasts in C. elegans.

The paper identifies ETR-1/CELF1 as a regulator of neuroblast migration in C. elegans, showing its non-autonomous role in muscle cells and potential interaction with Wnt signaling.

This study identifies RHO-1 and RHGF-1 as negative regulators of growth cone protrusion and microtubule accumulation, acting downstream of UNC-6/Netrin signaling in C. elegans.

The paper identifies 24 genes affecting luminal diameter in C. elegans excretory canals through a reverse genetic screen, revealing roles in cytoskeletal regulation and vesicle transport.

This paper investigates how UNC-6/Netrin and its receptors UNC-5 and UNC-40/DCC regulate growth cone polarity, microtubule organization, and protrusion during axon guidance in C. elegans.

The paper shows that EXC-2 and IFA-4 intermediate filaments maintain the structure of C. elegans excretory canals by preventing swelling and guiding tubule growth.

This study identifies CHW-1 as an atypical Rho GTPase involved in axon guidance in C. elegans, showing its genetic interaction with SAX-3 and requirement for proper axon pathfinding.

This study identifies FMO-1, FMO-4, FMO-5, and EHBP-1 as new factors downstream of UNC-6/Netrin and Rac GTPases that inhibit growth cone protrusion during repulsive axon guidance in C. elegans.