Author

Katharina Hecklau

NeuroCure Cluster of ExcellenceORCID 0000-0002-7743-5366Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Busra Kilic· 1 shared Christoph HarmsiD· 1 shared Ferah YildirimiD· 1 shared Mustafa Hussain MehkaryiD· 1 shared Philipp Boehm‐SturmiD· 1 shared Stefan KochiD· 1 shared Susanne G. MuelleriD· 1 shared

Activity by Year

2020-2020 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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1 shared paperNeuroscience

Busra Kilic

Mutual co-authors in cluster

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1 paper

Recent·Most cited

Selective inhibition of histone deacetylase 1 and 3 improves motor phenotype and alleviates transcriptional dysregulation in Huntington's disease mice

Katharina Hecklau, Susanne G. Mueller, Stefan Koch, Mustafa Hussain Mehkary, Busra Kilic, Christoph Harms, Philipp Boehm‐Sturm, Ferah Yildirim

This study shows that inhibiting HDAC1 and HDAC3 with RGFP109 improves motor function and corrects gene expression in a Huntington's disease mouse model.

bioRxiv · Oct 13, 2020 · PreprintNeuroscience