Author

Ferah Yildirim

Charité – Universitätsmedizin BerlinORCID 0000-0003-2979-6623Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

Christoph HarmsiD· 2 shared Philipp Boehm‐SturmiD· 2 shared Stefan KochiD· 2 shared Susanne G. MuelleriD· 2 shared Alessandro D. Confettura· 1 shared Anna KarpovaiD· 1 shared Busra Kilic· 1 shared Carsten FinkeiD· 1 shared

Activity by Year

2020-2020 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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2 shared papersNeuroscience

Christoph HarmsORCID

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3 papers

Recent·Most cited

NeurosciencebioRxivPreprintNov 4, 2020

Vascular cognitive impairment in the mouse reshapes visual, spatial network functional connectivity.

Gerard R. Hall, Philipp Boehm‐Sturm, Ulrich Dirnagl…·Tracy D. Farr

The paper examines structural and functional connectivity changes in a mouse model of vascular cognitive impairment, finding altered network connectivity and behavioural deficits.

DOI 10.1101/2020.11.04.366294

mouseimaging

𝕏 PostBluesky

NeurosciencebioRxivPreprintOct 13, 2020

Selective inhibition of histone deacetylase 1 and 3 improves motor phenotype and alleviates transcriptional dysregulation in Huntington's disease mice

Katharina Hecklau, Susanne G. Mueller, Stefan Koch…·Ferah Yildirim

This study shows that inhibiting HDAC1 and HDAC3 with RGFP109 improves motor function and corrects gene expression in a Huntington's disease mouse model.

DOI 10.1101/2020.10.13.337154

mousebulk RNA-seq

𝕏 PostBluesky

NeuroscienceNeuropsychopharmacologyPeer-reviewedJul 29, 2020

Synaptic control of DNA-methylation involves activity-dependent degradation of DNMT3a1 in the nucleus

Gonca Bayraktar, PingAn Yuanxiang, Alessandro D. Confettura…·Michael R. Kreutz

This study shows that synaptic activity controls DNA methylation by degrading DNMT3a1 via NMDAR-dependent neddylation.

27 citations

mouseDNA methylation

𝕏 PostBluesky