GenomicsbioRxivPreprint
Frequent Whole-Genome Duplication Events Drive the Genomic Evolution of Triple-Negative Breast Cancer During Neoadjuvant Chemotherapy
Devin P Bendixsen, Fiona Semple, Alastair J. Ironside…·Olga Oikonomidou
This study tracks genomic changes in TNBC during neoadjuvant chemotherapy, finding that whole-genome duplication events drive structural alterations and contribute to tumor evolution and response to treatment.
DOI 10.1101/2025.11.17.688693