Author

O’Connor J. Matthews

University of UtahORCID 0000-0002-7764-7959Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Organism:E. coli· 2 Approach:Bayesian inference· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Assay:metagenomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Matthew A. MulveyiD· 2 shared William J. BrazeltoniD· 2 shared Alan T. Stenquist· 1 shared Alejandra A. Mendez· 1 shared Bonkowsky Sam· 1 shared Brittany A. Fleming· 1 shared Edgar Javier HernandeziD· 1 shared Elijah R. Bring HorvathiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersMicrobiology

Matthew A. MulveyORCID

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2 papers

Recent·Most cited

MicrobiologybioRxivPreprintJul 28, 2026

The Small RNA MicC is a Multifunctional Regulator of Extraintestinal Pathogenic Escherichia coli Fitness across Multiple Host Niches

O’Connor J. Matthews, Brittany A. Fleming, Alejandra A. Mendez…·Matthew A. Mulvey

This paper identifies MicC as a multifunctional regulator of ExPEC fitness and virulence across host niches by modulating multiple pathways beyond its known target OmpC.

DOI 10.64898/2026.07.27.741068

E. colibulk RNA-seq

MicrobiologybioRxivPreprintOct 10, 2025

Global Footprint of the Multidrug Resistance Island Ec17R and Resistance Gene Co-Occurrence in Pathogenic Escherichia coli Isolates

Elijah R. Bring Horvath, O’Connor J. Matthews, William J. Brazelton…·Matthew A. Mulvey

The paper tracks a multidrug-resistant E. coli lineage over years, identifies a globally distributed resistance island, and finds resistance gene co-occurrence networks and antibiotic tolerance in isolates lacking known resistance mechanisms.

DOI 10.1101/2025.10.10.681733

E. colimetagenomics