Matthew A. Mulvey

This study identifies a synergistic combination of nitrofurantoin and dequalinium that effectively treats antibiotic-resistant Klebsiella pneumoniae in UTIs by targeting bacterial metabolism.

This paper identifies MicC as a multifunctional regulator of ExPEC fitness and virulence across host niches by modulating multiple pathways beyond its known target OmpC.

The paper tracks a multidrug-resistant E. coli lineage over years, identifies a globally distributed resistance island, and finds resistance gene co-occurrence networks and antibiotic tolerance in isolates lacking known resistance mechanisms.

ReGAIN identifies and maps resistance gene networks in bacterial pathogens using Bayesian networks, providing insights into co-occurrence patterns and antimicrobial resistance dynamics.