BioinformaticsbioRxivPreprint
Longitudinal Phylogenetic Inference of Copy Number Alterations and Single Nucleotide Variants from Single-Cell Sequencing
Ethan Kulman, Quaid Morris, Rui Kuang
LoPhy reconstructs the joint evolution of SNVs and CNAs from longitudinal single-cell data, revealing their roles in AML progression and therapy resistance.
DOI 10.1101/2025.09.16.676596