Xinyi Lin

This study uses mitochondrial variants as barcodes to track clonal dynamics and spatial organization in human hematopoietic organoids.

scRecover imputes dropout zeros in scRNA-seq data while preserving true zeros, improving downstream analysis through accurate zero discrimination.

This paper introduces a framework that enhances LLMs with gene-related tasks using retrieval-augmented generation and MMR algorithm, showing improved performance in gene question answering, cell type annotation, and gene interaction prediction.

scDecouple separates true cellular response from gRNA infection bias in scCRISPR-seq data, improving gene perturbation analysis in heterogeneous samples.

DCATS performs differential composition analysis for complex single-cell experiments, maintaining high sensitivity and specificity compared to existing methods.