Pharmacology & ToxicologybioRxivPreprint
The Oral Bioavailability of Lurasidone is Impacted by Changes to the Gut Microbiome: Implications for Antipsychotic Therapy
Kate Collins, Srinivas Kamath, Tahlia R. Meola…·Paul Joyce
This study shows that gut microbiome changes affect lurasidone bioavailability in rats, with prebiotics increasing it 4.3-fold and antibiotics reducing it in 80% of animals.
6 citations