Interplay of IGF1R and estrogen signaling regulates hematopoietic stem and progenitor cells
Ying Xie, Dongxi Xiang, Xin Hu, Hubert Pakula, Eunsil Park, Jiadong Chi, Douglas E. Linn, Luwei Tao, Zhe Li
This study shows that IGF1R and estrogen signaling interact to regulate HSPC proliferation, with sex-specific effects observed in adult and fetal hematopoiesis.
bioRxiv · Mar 20, 2024 · PreprintCell Biology