Dongxi Xiang

This study shows that RUNX1 loss in ER+ breast cancer promotes immune-active tumor formation through interferon signaling activation.

This study shows that LSD1 ablation in mammary tumor cells reduces NK cell-mediated anti-tumor immunity, leading to increased lung metastasis.

This study shows that IGF1R and estrogen signaling interact to regulate HSPC proliferation, with sex-specific effects observed in adult and fetal hematopoiesis.