Molecular BiologybioRxivPreprint
Senescence suppresses the integrated stress response and activates a stress-enhanced secretory phenotype
Matthew John Payea, Showkat Ahmad Dar, Carlos Anerillas…·Manolis Maragkakis
The paper investigates how senescence affects the integrated stress response and secretory phenotype in human cells, finding that translational repression of ATF4 reduces stress response and enhances inflammation.
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