Author

Florin C. Walter

German Cancer Research CenterORCID 0000-0002-7865-1749Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Approach:statistical model· 3 Research Focus:dimensionality reduction· 2 Organism:human· 2 Assay:spatial transcriptomics· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:CITE-seq· 1

Frequent Co-Authors

Oliver StegleiD· 3 shared Agnese LodaiD· 1 shared Arber QokuiD· 1 shared Britta VelteniD· 1 shared Carlotta Mantel PestanaiD· 1 shared David Palmero-CantoniD· 1 shared Duncan T. OdomiD· 1 shared Édith HeardiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersBioinformatics

Oliver StegleORCID

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3 papers

Recent·Most cited

Female specific erosion of allelic fidelity in aged CD8 memory T cells

Stefania Prete, Carlotta Mantel Pestana, Jasper Panten, Florin C. Walter, David Palmero-Canton, Francesca Coraggio, Agnese Loda, Édith Heard, Oliver Stegle, Duncan T. Odom

The paper shows that aged female CD8 memory T cells exhibit erosion of Xi transcriptional fidelity, linked to immune activation and clonal expansion, with similar findings in humans.

bioRxiv · Aug 28, 2026 · PreprintGenomics

MOFA-FLEX: A Factor Model Framework for Integrating Omics Data with Prior Knowledge

Arber Qoku, Martin Rohbeck, Florin C. Walter, Ilia Kats, Oliver Stegle, Florian Buettner

MOFA-FLEX is a flexible factor analysis framework that integrates multi-omics data with prior knowledge, improving robustness and disentangling variation in scRNA-seq and CITE-seq data.

bioRxiv · Nov 3, 2025 · PreprintBioinformatics

FISHFactor: A Probabilistic Factor Model for Spatial Transcriptomics Data with Subcellular Resolution

Florin C. Walter, Oliver Stegle, Britta Velten

FISHFactor is a probabilistic factor model for spatial transcriptomics data that improves accuracy by modeling single molecule resolution data and sharing information across cells.

Bioinformatics · Apr 11, 2023Peer-reviewedBioinformatics