Ray W. Turner

A somatic afterhyperpolarization is driven by ion channel nodes expressed across a polygonal spectrin cytoskeleton

The paper identifies a structured distribution of CaRyK ion channel clusters aligned with the spectrin cytoskeleton at the soma, contributing to the slow afterhyperpolarization.

Calcium-dependent regulation of neuronal excitability is rescued in Fragile X Syndrome by a tat-conjugated N-terminal fragment of FMRP

This study identifies a Cav3-Kv4 complex regulated by FMRP that controls neuronal excitability, and shows that FMRP-N-tat peptide treatment rescues this function in Fragile X Syndrome models.