BiophysicsNucleic Acids ResearchPeer-reviewed
Single-molecule Mechanostructural Fingerprinting of Nucleic Acid Conformations
Prakash Shrestha, Hans Bergal, William M. Shih, Wesley P. Wong
The paper introduces a DNA nanoswitch calipers platform to simultaneously measure structural and mechanical properties of biomolecules, demonstrating its application on telomeric DNA G-quadruplexes.