Author

Alessandro Morea

King's College LondonORCID 0000-0002-7919-1932Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Amy L. RobertsiD· 2 shared Ariella Amar· 2 shared Claire Joanne StevesiD· 2 shared Kerrin S. SmalliD· 2 shared Timothy James VyseiD· 2 shared Antonino ZitoiD· 1 shared Aparajita Sahoo· 1 shared Chloe C. Y. WongiD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersGenetic & Genomic Medicine

Amy L. RobertsORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Diminished sex hormone levels influence the risk of skewed X chromosome inactivation

Amy L. Roberts, Marc F. Österdahl, Aparajita Sahoo, Joseph Pickles, Christopher Franklin-Cheung, Samuel Wadge, Nawal A Mohamoud, Alessandro Morea, Ariella Amar, David Lester Morris, Timothy James Vyse, Claire Joanne Steves, Kerrin S. Small

The paper investigates the association between menopause and XCI-skew in females, finding early surgical menopause and low testosterone polygenic scores increase XCI-skew risk.

medRxiv · Apr 22, 2026 · PreprintGenetic & Genomic Medicine

Age acquired skewed X Chromosome Inactivation is associated with adverse health outcomes in humans

Amy L. Roberts, Alessandro Morea, Ariella Amar, Antonino Zito, Julia S. El-Sayed Moustafa, Max Tomlinson, Ruth C. E. Bowyer, Xinyuan Zhang, Colette Christiansen, Ricardo Costeira, Claire Joanne Steves, Massimo Mangino, Jordana T. Bell, Chloe C. Y. Wong, Timothy James Vyse, Kerrin S. Small

This study shows that age-related skewed X chromosome inactivation in females is linked to increased cardiovascular disease risk and cancer incidence.

eLife · Nov 1, 2022Peer-reviewedGenetic & Genomic Medicine