Author

Chloe C. Y. Wong

King's College LondonORCID 0000-0003-4886-8506Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 2 Genetic & Genomic Medicine· 1 Genetics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:human· 5 Approach:statistical model· 5 Research Focus:differential expression· 4 Assay:bulk RNA-seq· 3 Assay:DNA methylation· 3 Research Focus:gene regulatory network inference· 3 Assay:ChIP-seq· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Antonino ZitoiD· 2 shared Daniel H. GeschwindiD· 2 shared Gokul RamaswamiiD· 2 shared Jonathan S. MilliD· 2 shared Jordana T. BelliD· 2 shared Kerrin S. SmalliD· 2 shared Shyam PrabhakariD· 2 shared Wenjie Sun· 2 shared

Activity by Year

2019-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersGenetic & Genomic Medicine

Antonino ZitoORCID

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5 papers

Recent·Most cited

NeurosciencebioRxivPreprintJan 10, 2025

Epigenome-wide analysis reveals novel DNA methylation signatures significantly associated with the infant pupillary light reflex, a candidate intermediate phenotype for autism.

Laurel Alexandra Fish, Teodora Gliga, Anna Gui…·Chloe C. Y. Wong

The paper performs an epigenome-wide analysis of DNA methylation in infants to identify associations with the pupillary light reflex, finding novel methylation signatures linked to PLR latency and amplitude.

DOI 10.1101/2025.01.10.632385

humanDNA methylation

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Genetic & Genomic MedicineeLifePeer-reviewedNov 1, 2022

Age acquired skewed X Chromosome Inactivation is associated with adverse health outcomes in humans

Amy L. Roberts, Alessandro Morea, Ariella Amar…·Kerrin S. Small

This study shows that age-related skewed X chromosome inactivation in females is linked to increased cardiovascular disease risk and cancer incidence.

40 citationstop 4%

humanbulk RNA-seq

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GenomicsNature CommunicationsPeer-reviewedSep 25, 2020

Integrative genomics identifies a convergent molecular subtype that links epigenomic with transcriptomic differences in autism

Gokul Ramaswami, Hyejung Won, Michael J. Gandal…·Daniel H. Geschwind

The paper identifies a convergent molecular subtype in ASD by integrating epigenomic and transcriptomic data, revealing shared dysregulation and links to immune processes and genetic risk variants.

113 citationstop 1%

humanbulk RNA-seq

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GeneticsNature CommunicationsPeer-reviewedNov 25, 2019

Heritability of skewed X-inactivation in female twins is tissue-specific and dependent on age

Antonino Zito, Matthew N. Davies, Pei-Chien Tsai…·Kerrin S. Small

This study quantifies XCI skewing in female twins across tissues, showing age- and tissue-specific heritability and associations with smoking in older females.

74 citationstop 4%

humanbulk RNA-seq

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GenomicsHuman Molecular GeneticsPeer-reviewedMar 7, 2019

Genome-wide DNA methylation profiling identifies convergent molecular signatures associated with idiopathic and syndromic forms of autism in postmortem human brain tissue.

Chloe C. Y. Wong, Rebecca G. Smith, Eilis J. Hannon…·Jonathan S. Mill

98 citationstop 2%

humanDNA methylation

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