Elvezia Maria Paraboschi

Modeling polygenic embryo screening in real-world IVF patients demonstrates limitations on efficacy

This paper models polygenic embryo screening (PES) in IVF patients and finds it leads to small relative risk reductions in most cases due to low live birth rates and limited embryo availability.

Maternal age and genome-wide failure of meiotic recombination are associated with triploid conceptions in humans

The paper investigates the association between maternal age and meiotic recombination failure with triploid/haploid conceptions in humans, identifying a maternal age effect and new types of genome-wide maternal isodiploidy.

ACE2 and TMPRSS2 variants and expression as candidates to sex and country differences in COVID-19 severity in Italy

The paper investigates ACE2 and TMPRSS2 variants and expression levels in relation to sex and country differences in COVID-19 severity in Italy, finding TMPRSS2 as a potential modulator.