Author

Genevieve Ray Lyons

Brigham and Women's HospitalORCID 0000-0002-7936-6210Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:benchmarking· 1 Assay:GWAS summary statistics· 1 Organism:human· 1 Approach:machine learning (classical)· 1 Research Focus:polygenic risk· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Alanna C. MorrisoniD· 1 shared Bruce M. PsatyiD· 1 shared Daniel A LevyiD· 1 shared Donald M. Lloyd‐JonesiD· 1 shared Gina Marie PelosoiD· 1 shared Han CheniD· 1 shared Henry J. LiniD· 1 shared Jennifer A. BrodyiD· 1 shared

Activity by Year

2022-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperGenetic & Genomic Medicine

Alanna C. MorrisonORCID

Mutual co-authors in cluster

Author profile →

1 paper

Recent·Most cited

Genetic & Genomic MedicineCommunications BiologyPeer-reviewedAug 22, 2022

Polygenic Risk Prediction using Gradient Boosted Trees Captures Non-Linear Genetic Effects and Allele Interactions in Complex Phenotypes

Michael Elgart, Genevieve Ray Lyons, Santiago Romero Brufau…·Tamar Sofer

This paper uses gradient boosted trees to improve polygenic risk prediction by capturing non-linear genetic effects and SNP interactions, showing significant increases in variance explained for multiple complex traits.

114 citationstop 1%

humanGWAS summary statistics

𝕏 PostBluesky