The myeloid cell-driven transdifferentiation of endothelial cells into pericytes promotes the restoration of BBB function and brain self-repair after stroke
Tingbo Li, Ling Yang, Jiaqi Tu, Yufan Hao, Zhu Zhu, Yingjie Xiong, Qingzhu Gao, Lili Zhou, Guanglei Xie, Dongdong Zhang, Xuzhao Li, Yuxiao Jin, Yiyi Zhang, Bingrui Zhao, Nan Li, , Jie-Min Jia
This study shows that myeloid cell-driven transdifferentiation of endothelial cells into pericytes helps restore BBB function and brain repair after stroke.
eLife · Jul 16, 2025Peer-reviewedNeuroscience