Cancer Biologynpj Breast CancerPeer-reviewed
Reprogramming breast cancer cells to breast cancer stem cell-like by the POU1F1 transcription factor
Leandro Ávila, Samuel Seoane, Sandra Paola Rodríguez-González…·Román Pérez-Fernández
This study shows POU1F1 reprograms breast cancer cells into BCSC-like by altering key markers and activating the IL-6/JAK2/STAT3 pathway, suggesting therapeutic targeting of this pathway in hormone therapy-resistant tumors.
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