Inhibition of the mitochondrial pyruvate carrier attenuates the integrated stress response activation in a cellular model of Huntington's disease
Ângela Z. Oliveira, Liliana M. Almeida, Jorge M. A. Oliveira, Brígida R. Pinho
This study shows that inhibiting the mitochondrial pyruvate carrier modulates the integrated stress response differently in wild-type and mutant huntingtin-expressing cells.
Molecular and Cellular Biochemistry · May 21, 2026Peer-reviewedPharmacology & Toxicology