Author

Daniel M. Cohen

University of PennsylvaniaORCID 0000-0002-7963-668XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

A. MetziD· 1 shared Ahil N. Ganesh· 1 shared Cameron Baptista· 1 shared David J. StegeriD· 1 shared Federico MingozziiD· 1 shared Hee‐Woong LimiD· 1 shared Joseph Silverberg· 1 shared Kyoung‐Jae WoniD· 1 shared

Activity by Year

2018-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperSynthetic Biology

A. MetzORCID

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2 papers

Recent·Most cited

Tunable Expression of an AAV Payload Using ADAR-mediated RNA Editing

Joseph Silverberg, Laura Pereira, Robert Schmidt, Cameron Baptista, Ahil N. Ganesh, Nicole Harbaugh, Lauren Moffa, A. Metz, Victor Howard, Sean Armour, Daniel M. Cohen, Federico Mingozzi

This paper demonstrates an ADAR-mediated gene switch to control AAV-delivered gene expression by rescuing a premature termination codon via RNA editing, achieving tunable and clinically relevant therapeutic protein levels.

bioRxiv · Aug 5, 2026 · PreprintSynthetic Biology

Shared Nucleotide Flanks Confer Transcriptional Competency to bZip Core Motifs

Daniel M. Cohen, Hee‐Woong Lim, Kyoung‐Jae Won, David J. Steger

The paper identifies how flanking nucleotides influence CEBP binding and transcriptional activity, revealing sequence biases and heterodimerization effects in mammalian bZip TFs.

Nucleic Acids Research · Jul 18, 2018Peer-reviewedGenomics