Mosaic deletion patterns of the human antibody heavy chain gene locus as revealed by Bayesian haplotyping
Moriah Gidoni, Omri Snir, Ayelet Peres, Pazit Polak, Ida Lindeman, Ivana Mikocziova, Vikas K. Sarna, Knut E. A. Lundin, Christopher R. Clouser, François Vigneault, Andrew M. Collins, Ludvig Magne Sollid, Gur Yaari
The paper develops a Bayesian haplotyping method to infer V-D-J haplotypes and deletion patterns in the human antibody heavy chain gene locus using antibody repertoire sequencing data.
Nature Communications · Feb 7, 2019Peer-reviewedGenomics