Knut E. A. Lundin

The paper examines systemic and gut IgA responses to bacteria in the human upper gastrointestinal tract, finding distinct reactivity patterns and limited clonal overlap between gut and bone marrow plasma cells.

The paper shows HLA-DQ2.5 variants increase frequencies of TCR genes involved in gluten epitope recognition in CeD patients, linking HLA to disease by shaping the naive TCR repertoire.

This study identifies gene expression patterns and eQTLs in duodenal epithelial lining of coeliac disease patients that reflect inflammation status and disease condition.

This study identifies 13 novel genetic associations for celiac disease, with the 5p15.33 locus showing strong potential, and links IRX1 to rheumatoid arthritis.

The paper develops a Bayesian haplotyping method to infer V-D-J haplotypes and deletion patterns in the human antibody heavy chain gene locus using antibody repertoire sequencing data.