Pazit Polak

The paper develops methodologies to generate and analyze immunoglobulin loci variation in rhesus macaques, revealing extensive diversity and expanding existing allele sets by 60%.

The paper introduces GenAIRR, a simulation framework for Ig sequences, and evaluates aligners to identify their performance characteristics, establishing a benchmarking standard for Ig sequence alignment.

The paper develops a Bayesian haplotyping method to infer V-D-J haplotypes and deletion patterns in the human antibody heavy chain gene locus using antibody repertoire sequencing data.