Cohesin guides homology search during DNA repairvia loops and sister chromatid linkages
Federico Teloni, Zsuzsanna Takács, Michael Mitter, Christoph C. H. Langer, Inès Prlesi, Thomas L. Steinacker, Vincent P. Reuter, Dmitry Evgenevich Mylarshchikov, Daniel W. Gerlich
This study reveals how cohesin facilitates homology search during DNA repair by reshaping chromosome architecture through two distinct cohesin pools.
bioRxiv · Feb 10, 2025 · PreprintCell Biology