Daniel W. Gerlich

The paper reveals a genome-wide asymmetry in sister chromatid alignment due to replication fork asymmetry, maintained by cohesive cohesins.

The paper shows cohesin function is partitioned within the TAD hierarchy to form cohesion zones and enable sister-chromatid cohesion while preserving loop folding.

This study shows that electrostatic attraction compacts fragmented DNA during apoptosis, preventing its release, and demonstrates a synthetic approach to probe physical forces in genome organization.

This study identifies electrostatic repulsion as the mechanism driving centromere positioning at the chromatin surface, independent of condensin or microtubules.

This study reveals how cohesin facilitates homology search during DNA repair by reshaping chromosome architecture through two distinct cohesin pools.

The paper identifies PP2A-B55alpha,delta phosphatase as counteracting Ki67-dependent chromosome individualization during mitosis in mice.

HiCognition enables visual exploration and hypothesis testing of 3D genomic structure by integrating 1D genomics profiles and machine learning.