Author

Gerry P. Crossan

MRC Laboratory of Molecular BiologyORCID 0000-0002-7974-009XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Organism:mouse· 1

Frequent Co-Authors

Juan I. GaraycoecheaiD· 2 shared Abdulkadir AbakiriD· 1 shared Camille DioniD· 1 shared Eleni Stefoudi· 1 shared Hannah K. WebbiD· 1 shared Harry G. LeitchiD· 1 shared Jeroen Willems· 1 shared Job Smink· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersMolecular Biology

Juan I. GaraycoecheaORCID

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2 papers

Recent·Most cited

Mechanistically distinct BER processes are essential for the tolerance of exogenous 5hm-dC and enzymatic oxidative demethylation

Job Smink, Hannah K. Webb, Eleni Stefoudi, Ross Hill, Michael A. Terzidis, Gerry P. Crossan, Juan I. Garaycoechea

The paper investigates the cellular consequences of exogenous 5hm-dC and endogenous oxidative demethylation, revealing distinct BER processes required for tolerance.

bioRxiv · Aug 21, 2026 · PreprintMolecular Biology

Primordial germ cell DNA demethylation and development require DNA translesion synthesis.

Pranay Shah, Ross J. Hill, Camille Dion, Stephen J. Clark, Abdulkadir Abakir, Jeroen Willems, Mark Johan Arends, Juan I. Garaycoechea, Harry G. Leitch, Wolf Reik, Gerry P. Crossan

The paper shows that DNA translesion synthesis is essential for primordial germ cell development and DNA demethylation in mammals, linking DDR to fertility.

Nature Communications · May 3, 2024Peer-reviewedDevelopmental Biology