Cardiac fibroblast GSK-3α mediates adverse myocardial fibrosis via IL-11 and ERK pathway
Prachi Umbarkar, Sultan Tousif, Anand Prakash Singh, Joshua Charles Anderson, Qinkun Zhang, Hind Lal
This study identifies GSK-3α in cardiac fibroblasts as a mediator of myocardial fibrosis through the IL-11 and ERK pathway, showing its role in fibroblast activation and cardiac function improvement upon deletion.
bioRxiv · Feb 2, 2021 · PreprintMolecular Biology