Cancer BiologybioRxivPreprint
Integrative pipeline to profile and target endocrine therapy-insensitive cell populations in ER+ breast cancer
Svetlana E. Semina, Rosemary J. Huggins, Huiping Zhao…·Jonathan L. Coloff
The paper develops an analytical pipeline to identify and target endocrine therapy-insensitive cells in ER+ breast cancer using single-cell RNA sequencing and functional validation in organoid models.