Characterization of Human Anterior Neural Organoids as a Model for Investigating Cohen Syndrome
Renuka Prasad, Ju‐Hyun Lee, Da‐Yeon Lee, Yeonhee Lee, Jihae Lee, Si-Hyung Park, Jae Ryun Ryu, Boram Lee, Seungji Choi, Jungmin Choi, Il‐Joo Cho, Joon‐Yong An, Fabrizio Vacca, Muhammad Ansar, Hyun Jung Kim, , Woong Sun
This study develops a method to generate human anterior neural organoids (hANOs) and uses them to model microcephaly in Cohen syndrome by analyzing gene expression and cellular phenotypes.
bioRxiv · Apr 23, 2025 · PreprintNeuroscience