Il‐Joo Cho

This study develops a method to generate human anterior neural organoids (hANOs) and uses them to model microcephaly in Cohen syndrome by analyzing gene expression and cellular phenotypes.

This study develops multi-region 3D neural probe arrays to record functional connectivity in thick acute mouse brain slices, showing improved single-unit signal detection compared to conventional slices.

This study generates a polarized spinal cord-like organoid with dorsoventral organization using geometrically confined hPSC cultures and shows that BMP and Shh signaling control DV patterning.

This study shows that astrocytic urea cycle detoxifies Aβ-derived ammonia but impairs memory in Alzheimer's disease, suggesting ODC1 inhibition as a potential therapeutic strategy.