Author

Andrew Josef Severin

Iowa State UniversityORCID 0000-0002-8015-9665Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Assay:whole-genome sequencing· 4 Approach:statistical model· 3 Research Focus:gene regulatory network inference· 2 Research Focus:genome assembly· 2 Organism:bacteria (other)· 1 Assay:bulk RNA-seq· 1 Organism:C. elegans· 1

Frequent Co-Authors

Rick E. MasonbrinkiD· 4 shared David P. AltiD· 2 shared Sivanandan ChudalayandiiD· 2 shared Steven C. OlseniD· 2 shared Usha K. MuppiralaiD· 2 shared Aleksandra Elzbieta Badaczewska-DawidiD· 1 shared Aleksey V. ZiminiD· 1 shared Amanda R. StahlkeiD· 1 shared

Activity by Year

2019-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersBioinformatics

Rick E. MasonbrinkORCID

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Recurrent Duplication of the REST-NOA1 Locus Reveals a Hotspot of Regulatory Evolution Across Even-Toed Ungulates

Rick E. Masonbrink, Sharu Paul Sharma, Viswanathan Satheesh, Aleksandra Elzbieta Badaczewska-Dawid, Sivanandan Chudalayandi, David P. Alt, Paola Boggiatto, Ellie J. Putz, Andrew Josef Severin, Steven C. Olsen

The paper identifies recurrent duplication of the REST-NOA1 locus in ungulates and shows how structural divergence and regulatory changes contribute to immune system evolution.

bioRxiv · Jun 26, 2026 · PreprintBioinformatics

polishCLR: a Nextflow workflow for polishing PacBio CLR genome assemblies

Jennifer Chang, Amanda R. Stahlke, Sivanandan Chudalayandi, Benjamin D. Rosen, Anna K. Childers, Andrew Josef Severin

polishCLR is a Nextflow workflow for polishing PacBio CLR genome assemblies using best practices, improving accuracy through multiple polishing rounds and evaluation tools.

Genome Biology and Evolution · Feb 15, 2023Peer-reviewedBioinformatics

A pseudomolecule assembly of the Rocky Mountain elk genome reveals putative immune system gene loss near chromosomal fissions

Rick E. Masonbrink, David P. Alt, Darrell O. Bayles, Paola Mercedes Boggiatto, William H. Edwards, Fred M. Tatum, Jeffrey T. Williams, Jennifer H. Wilson‐Welder, Aleksey V. Zimin, Andrew Josef Severin, Steven C. Olsen

The paper assembles the Rocky Mountain elk genome and identifies nine putative immune system gene losses compared to cattle.

bioRxiv · Sep 30, 2020 · PreprintGenomics

Shared Data Science Infrastructure for Genomics Data

Hamid Bagheri, Usha K. Muppirala, Rick E. Masonbrink, Andrew Josef Severin, Hridesh Rajan

The paper introduces BoaG, a data science infrastructure for genomic research, demonstrating its ability to efficiently explore RefSeq data and reveal species-specific assembly quality variations.

BMC Bioinformatics · Aug 22, 2019Peer-reviewedBioinformatics

The genome of the soybean cyst nematode (Heterodera glycines) reveals complex patterns of duplications involved in the evolution of parasitism genes

Rick E. Masonbrink, Tom R. Maier, Usha K. Muppirala, Arun Somwarpet Seetharam, Étienne Lord, Parijat S. Juvale, Jeremy Schmutz, Nathan T. Johnson, Dmitry Korkin, Melissa Goellner Mitchum, Benjamin Mimee, Sebastian Eves‐van den Akker, Matthew E. Hudson, Andrew Josef Severin, Thomas J. Baum

The paper assembles and annotates the genome of the soybean cyst nematode, revealing duplications and horizontal gene transfer events in effector genes involved in parasitism.

BMC Genomics · Feb 7, 2019Peer-reviewedGenomics