Author

Ismail Mohammed Shakir

King Abdullah University of Science and TechnologyORCID 0000-0002-8026-9549Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:clustering· 2 Organism:human· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Arun Pandian ChandrasekaraniD· 2 shared Mo LiiD· 2 shared Yingzi ZhangiD· 2 shared Yiqing JiniD· 2 shared Aisha SiddiqueiD· 1 shared Alfonso Saera-VilaiD· 1 shared Baolei YuaniD· 1 shared Gerardo Ramos‐MandujanoiD· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersDevelopmental Biology

Arun Pandian ChandrasekaranORCID

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2 papers

Recent·Most cited

deepBlastoid: A Deep Learning-Based High-Throughput Classifier for Human Blastoids Using Brightfield Images with Confidence Assessment

Zejun Fan, Zhenyu Li, Yiqing Jin, Arun Pandian Chandrasekaran, Ismail Mohammed Shakir, Yingzi Zhang, Aisha Siddique, Mengge Wang, Xuan Zhou, Yeteng Tian, Peter Wonka, Mo Li

deepBlastoid is a deep learning model that classifies human blastoid brightfield images into quality categories with high accuracy and throughput, outperforming human experts in speed while matching their accuracy.

bioRxiv · Dec 5, 2024 · PreprintDevelopmental Biology

DMSO derives Trophectoderm and Clonal Blastoid from Single Human Pluripotent Stem Cell

Samhan M. Alsolami, Arun Pandian Chandrasekaran, Yiqing Jin, Ismail Mohammed Shakir, Yingzi Zhang, Gerardo Ramos‐Mandujano, Baolei Yuan, Alfonso Saera-Vila, Juan Carlos Izpisúa Belmonte, Mo Li

This study shows that DMSO induces trophectoderm differentiation and blastoid formation from single human pluripotent stem cells without additional perturbations.

bioRxiv · Dec 31, 2023 · PreprintDevelopmental Biology