Author

Louis Dumas

École Polytechnique Fédérale de LausanneORCID 0000-0002-8044-7683Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1

Frequent Co-Authors

Amédé Larabi· 1 shared Aurélien Oggier· 1 shared Byeongseon YangiD· 1 shared Florence PojeriD· 1 shared Kelvin LauiD· 1 shared M. MarfogliaiD· 1 shared Mahdi HijaziiD· 1 shared Melinda Pedraza· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiophysics

Amédé Larabi

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1 paper

Recent·Most cited

Molecular characterization of an adhesion GPCR signal transduction

M. Marfoglia, Louis Dumas, Byeongseon Yang, Aurélien Oggier, Melinda Pedraza, Mahdi Hijazi, Amédé Larabi, Kelvin Lau, Florence Pojer, Michael A. Nash, P. Barth

This study investigates ADGRG1 activation mechanisms through mechanical and allosteric pathways, showing force direction determines signaling via GAIN domain dynamics and introducing engineered variants with tailored sensitivity.

bioRxiv · Aug 14, 2025 · PreprintBiophysics