Author

Minwoo Baek

University of MinnesotaORCID 0000-0002-8051-8082Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Organism:Drosophila· 2 Approach:experimental assay· 2 Organism:human· 1

Frequent Co-Authors

Nam Chul KimiD· 2 shared Yun-Jeong Choe· 2 shared Gerald W. DorniD· 1 shared J. Paul TayloriD· 1 shared Swati Maitra· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 8 mutual co-author links

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2 shared papersNeuroscience

Nam Chul KimORCID

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintJun 4, 2024

FDA approved PDE4 inhibitors reduce the dominant toxicity of ALS/FTD associated CHCHD10S59L

Swati Maitra, Minwoo Baek, Yun-Jeong Choe, Nam Chul Kim

The paper shows FDA-approved PDE4 inhibitors reduce mitochondrial defects and toxicity caused by CHCHD10S59L mutations in human cells and Drosophila models.

DOI 10.1101/2024.06.04.597429

Drosophilahuman

𝕏 PostBluesky

NeurosciencebioRxivPreprintSep 3, 2019

Dominant toxicity of ALS-FTD-associated CHCHD10S59L is mediated by TDP-43 and PINK1

Minwoo Baek, Yun-Jeong Choe, Gerald W. Dorn…·Nam Chul Kim

The paper shows that CHCHD10S59L causes mitochondrial toxicity in Drosophila and HeLa cells, which can be mitigated by inhibiting TDP-43 mitochondrial translocation or PINK1 kinase activity.

2 citations

Drosophilaexperimental assay

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