Cancer BiologybioRxivPreprint
Dual inhibition of p38α MAPK and Casein kinase δ/ϵ as a novel treatment strategy for AR-independent and taxane-resistant advanced prostate cancer
Sayak Chakravarti, Suman Mazumder, Farnaz Hemmati…·Amit Mitra
This paper demonstrates that TAK-715, a dual inhibitor of p38α MAPK and casein kinase δ/ϵ, effectively treats taxane-resistant and aggressive prostate cancer by targeting cancer stemness and mitochondrial dysfunction.
DOI 10.64898/2026.09.29.754128