Molecular BiologyGenome biologyPeer-reviewed
FIRST-seq: a nanopore-based cDNA sequencing platform for RNA modification and structure profiling
Oguzhan Begik, Gregor Diensthuber, Ivana Borovská…·Eva Maria Novoa
FIRST-seq uses nanopore cDNA sequencing to profile RNA modifications and structures by analyzing RT errors, achieving single-nucleotide resolution without PCR or second-strand synthesis.
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