Making the best of a sticky situation: Infection-mediated endothelial activation promotes new interactions with adhesins of the host-adapted Lyme disease spirochete
Daiana Alvarez Olmedo, Xi Tan, Colton Scott, Aleksandra Shcherbakova, George Chaconas
This study identifies eleven new adhesins in Borrelia burgdorferi that mediate interactions with activated endothelial cells during infection, revealing a dynamic network involved in spirochete transmigration.
bioRxiv · Feb 21, 2026 · PreprintMicrobiology