Author

Upendra Katneni

Center for Biologics Evaluation and ResearchORCID 0000-0002-8145-8894Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:benchmark study· 1 Assay:DNA methylation· 1 Organism:human· 1 Approach:statistical model· 1 Research Focus:variant effect prediction· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Chava Kimchi‐SarfatyiD· 1 shared Christine MordsteiniD· 1 shared Eleanor R. GauntiD· 1 shared Fernando Bellido MolíasiD· 1 shared Grzegorz R. KudlaiD· 1 shared Laura Cano-Aroca· 1 shared Laurence D. HurstiD· 1 shared Marguerite J. Clarke· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperSynthetic Biology

Chava Kimchi‐SarfatyORCID

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1 paper

Recent·Most cited

Synthetic BiologybioRxivPreprintMay 25, 2026

Splice-Aware Optimization Prevents Pervasive Missplicing of Natural and Synthetic cDNAs

Mohd Ahmad, Fernando Bellido Molías, Laura Cano-Aroca…·Grzegorz R. Kudla

The paper identifies missplicing as a common issue in heterologous gene expression and develops a splice-aware optimization algorithm to improve transgene performance.

1 citation

humanDNA methylation

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