R-CHOP in B cell non-Hodgkin lymphoma: balancing anti-tumor efficacy and NK-cell functionality
Johanna Jansky, Hannah Breitung, Sylvia Zöphel, Laetitia Döngi, Florian Wentzel, Daniel J. Picard, Nadja Küchler, Hermann Eichler, Marc Remke, Moritz Bewarder, Lorenz Thurner, Gebhard Stopper, Eva C. Schwarz, Markus Hoth
This study evaluates the impact of R-CHOP chemotherapy on NK cell viability and function in DLBCL cell lines and patients, finding that treatment reduces NK cell numbers but preserves their cytotoxicity.
bioRxiv · Jul 23, 2026 · PreprintCancer Biology