Xin Liu

This study identifies reactive astrocytes controlled by Wnt5a signaling as critical for opioid-induced hyperalgesia development in mice.

This study shows that microglial ablation does not impair opioid-induced hyperalgesia in rodents, challenging the assumption of microglial involvement in this condition.

This study identifies a novel mechanism by which astrogliosis contributes to HIV-associated pain through Wnt5a signaling and IL-1β regulation.

This study uses scRNA-seq to compare microglia in adult mouse brains and spinal cords, identifying subtype differences and plasticity in response to HIV-1 gp120.