Author

Grażyna Adamek

Institute of Bioorganic Chemistry, Polish Academy of SciencesORCID 0000-0002-8233-1473Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Agata CiołakiD· 1 shared Agnieszka FiszeriD· 1 shared Albert R. La SpadaiD· 1 shared Court HulliD· 1 shared Craig B. LoweiD· 1 shared Daniel R. ScolesiD· 1 shared Emilia KozłowskaiD· 1 shared Harry T. OrriD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperNeuroscience

Agata CiołakORCID

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2 papers

Recent·Most cited

NeuroscienceCell & BiosciencePeer-reviewedJul 9, 2025

Huntingtin loss-of-function contributes to transcriptional deregulation in Huntington's disease

Emilia Kozłowska, Agata Ciołak, Grażyna Adamek…·Agnieszka Fiszer

This study identifies transcriptional deregulation in Huntington's disease by comparing HD and HTT-knockout cells, showing that loss of HTT function drives early transcriptional changes.

10 citations

humanbulk RNA-seq

GenomicsbioRxivPreprintMar 19, 2023

Purkinje-Enriched snRNA-seq in SCA7 Cerebellum Reveals Zebrin Identity Loss as a Central Feature of Polyglutamine Ataxias

Luke C. Bartelt, Pawel Michal Switonski, Grażyna Adamek…·Albert R. La Spada

The paper uses snRNA-seq to study Purkinje cells in SCA7 mice, revealing zebrin-II subtype loss as a key feature of polyglutamine ataxias.

7 citations

mousesnRNA-seq