Author
Duke UniversityORCID 0000-0001-8731-3680Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Schuyler M. Melore, D. Dewran Koçak, Keith Siklenka…·Timothy E. Reddy
The paper identifies SMARCA2 as a critical cofactor for a subset of glucocorticoid response genes in A549 cells through a CRISPR screen and functional analysis.
Matthew V. Green, David A. Gallegos, Jane-Valeriane K. Boua…·Anne E. West
The paper identifies molecular features of GAD2+/VGLUT2+ neurons in the mouse lateral habenula using single-nucleus RNA sequencing, revealing sex-specific gene expression and links to depression.
Luke C. Bartelt, Pawel Michal Switonski, Grażyna Adamek…·Albert R. La Spada
The paper uses snRNA-seq to study Purkinje cells in SCA7 mice, revealing zebrin-II subtype loss as a key feature of polyglutamine ataxias.
David A. Gallegos, Melyssa S. Minto, Fang Liu…·Anne E. West
The paper identifies cell-type specific transcriptional changes in PV+ interneurons of the nucleus accumbens in response to amphetamine exposure and links these changes to addictive-like behaviors.
Matthew P. Gemberling, Keith Siklenka, Erica Rodriguez…·Charles A. Gersbach
This paper describes the generation of two transgenic mouse lines for in vivo epigenome editing using CRISPR-based systems to activate or repress gene expression.