The addiction-susceptibility TaqIA/Ankyrin repeat and kinase domain containing 1 kinase (ANKK1) controls reward and metabolism through dopamine receptor type 2 (DR2)-expressing neurons
Enrica Montalban, Roman Walle, Julien Castel, Anthony Ansoult, Rim Hassouna, Ewout Foppen, Xi Fang, Zach Hutelin, Sophie Mickus, Emily E. Perszyk, Anna Petitbon, Jérémy Berthelet, Fernando Rodrigues‐Lima, Alberto Cebrian-Serrano, Giuseppe Gangarossa, , Serge H. Luquet
This study identifies ANKK1's role in striatal DR2-expressing neurons, linking it to reward, metabolism, and behaviors associated with the A1 allele of TaqIA.
Biological Psychiatry · Feb 16, 2023Peer-reviewedNeuroscience