Hillery C. Metz

Olfactory receptor coexpression and co-option in the dengue mosquito

The paper analyzes the transcriptomes of dengue mosquito neurons to show that olfactory receptors are coexpressed within families but not across families, revealing evolutionary patterns in olfactory systems.

Expression of endogenous Anopheles gambiae microRNAs using an Anopheles gambiae densovirus (AgDNV) intronic expression system

This paper develops an AgDNV intronic expression system to deliver microRNAs in Anopheles gambiae, showing variable miRNA target gene regulation.

The impact of systematized generation, evaluation, and incorporation of machine learning algorithms for clinical variant classification

The paper develops a machine learning platform to improve variant classification, reducing VUS rates and improving concordance with ClinVar submissions.

Function and evolution of aquaporin IsAQP1 in the Lyme disease vector Ixodes scapularis

This study identifies and functionally characterizes IsAQP1, an aquaporin in Ixodes scapularis, showing it is a water channel with low glycerol permeability and salivary gland-specific expression.