Author

Christian Kofoed

Princeton UniversityORCID 0000-0002-8258-5887Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:protein sequence· 2 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Tom W. MuiriD· 2 shared Xuanjia YeiD· 2 shared Anushka DheeriD· 1 shared Girum ErkaloiD· 1 shared Joshua SokoliD· 1 shared Juner ZhangiD· 1 shared Nicholas E. S. TayiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 15 mutual co-author links

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2 shared papersBiochemistry

Tom W. MuirORCID

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2 papers

Recent·Most cited

Traceless protein semi-synthesis in cells using the promiscuous ultra-fast split intein NrdJ-1

Xuanjia Ye, Joshua Sokol, Christian Kofoed, Anushka Dheer, Juner Zhang, Tom W. Muir

This paper characterizes the split intein NrdJ-1, showing its rapid and promiscuous splicing properties for traceless protein modification in vitro and in cells.

Chemical Science · Jan 1, 2026Peer-reviewedBiochemistry

Cell surface sculpting using logic-gated protein actuators

Christian Kofoed, Nicholas E. S. Tay, Xuanjia Ye, Girum Erkalo, Tom W. Muir

This paper introduces a protein actuator platform that performs Boolean logic operations on cell surfaces using proximity-gated trans-splicing, enabling selective recruitment of enzymatic and cytotoxic activities to specific cells.

bioRxiv · Dec 18, 2023 · PreprintSynthetic Biology