Hilde E. Groot

Federated single-cell QTL meta-analysis reveals novel disease mechanisms

The paper performs a federated cis-eQTL meta-analysis across single-cell datasets to identify cell-type-specific genetic effects and link them to disease mechanisms.

The gut microbiome across the cardiovascular risk spectrum

The paper examines gut microbiome changes across different cardiovascular risk levels and in STEMI patients, identifying microbial species and pathways associated with cardiovascular risk and disease.

Identification of genetic variants that impact gene co-expression relationships using large-scale single-cell data

The paper identifies co-expression QTLs (co-eQTLs) using single-cell RNA-seq data, revealing how genetic variants affect gene co-expression patterns and regulatory networks in specific cell types.