Sergio Andreu‐Sánchez

Prophages of infant-derived Bifidobacterium longum subspecies employ antagonistic and synergistic strategies to persist in their host

The paper identifies and analyzes prophages in infant-derived Bifidobacterium longum subspecies, revealing their antagonistic and synergistic strategies for persistence in the gut.

Discovery, functionality and global dynamics of Bifidobacterium longum subsp. nexti : a novel starch-degrading subspecies in the infant gut

The paper identifies a novel subspecies of Bifidobacterium longum, BL. nexti, in infant gut microbiomes, showing its association with formula feeding and vertical transmission.

The gut microbiome across the cardiovascular risk spectrum

The paper examines gut microbiome changes across different cardiovascular risk levels and in STEMI patients, identifying microbial species and pathways associated with cardiovascular risk and disease.

Unbiased identification of unknown cellular and environmental factors that mediate eQTLs using principal interaction component analysis

This paper introduces PICALO, a method to identify unknown contexts influencing eQTLs, finding 31 and 21 PICs in blood and brain datasets, respectively, associated with cell type, RNA quality, and environmental factors.

Effect of host genetics on the gut microbiome in 7,738 participants of the Dutch Microbiome Project

The paper identifies host genetic loci associated with gut microbiome composition and function in a large cohort, finding significant associations near LCT and ABO genes.

A comparison of tools for copy-number variation detection in germline whole exome and whole genome sequencing data

The paper benchmarks CNV detection tools on WGS and WES data using clinical standards and reference samples, finding that combining multiple tools improves recall but precision remains a challenge.